Academy of Medical Sciences of Islamic Republic of IranArchives of Iranian Medicine1029-29771312010JanuaryCarpal Tunnel Syndrome due to Lipofibromatous Hamartoma of the Median Nerve4547ENAhmadrezaAfsharDepartment of Orthopaedics, Urmia University of Medical Sciences, Urmia, Iran. afshar@umsu.ac.ir; Afshar_ah@yahoo.com 0011010131/AIM.0011This report describes a rare case of secondary carpal tunnel syndrome due to a lipofibromatous hamartoma of the median nerve. Excision of the fibrofatty tissue between the nerve fascicles without risking damage to the fascicles was impossible. The transverse carpal ligament was incised and an epineurotomy was performed. Within six months, the 25-year-old female patient’s symptoms were much improved.